Six men have been arrested following the seized of drugs over in Portadown and Armagh.
Police also uncovered drugs in the Magheralin, Donacloney and Rathfriland areas over the past 24 hours.
The seizures were in relation to the possession and supply of class A, B and C controlled substances.
Two of the six men have been arrested on suspicion of supplying drugs.
Chief Inspector Burrows said: “Drugs will not be tolerated.
“Dealers can expect to be searched, disrupted and brought to court. Alongside enforcement we are engaging with schools and young people about the dangers of drugs and we appeal to anyone with information about drug crime to contact the PSNI directly or Crimestoppers anonymously on 0800 555111.”