County Armagh pharmaceutical firm Almac has unveiled a £20m investment in Philadelphia as it continues to expand in America.
The company will also spend £5m on expanding its Craigavon headquarters with a new laboratory and office.
Almac also announced it was spending £2m on the Arran Chemical Company site in Athlone.
Almac Group chief executive Alan Armstrong said: “Due to significant industry demand for our services, it is essential we build capacity and increase headcount to ensure we continue to compete at a global level.
“This year we are celebrating our twentieth year in the US and we are excited to make a further commitment within the Pennsylvania state and throughout North America.
“We are also delighted to announce our further expansion plans across Europe as we continue to build upon our global success, and we are looking forward to an exciting future.”
Almac is now the biggest Northern Ireland firm to have major premises in America.